Abstract 132: Effect Of Ngf Delivering Conduit On Peripheral Nerve Regeneration

Sarday, M ay 6, 2017 PURPOSE: We recently developed a serum-free, ex vivo cell expansion system called Mononuclear Cell Quality and Quantity Control Culture System (MNC-QQc), using peripheral blood mononuclear cells (MNCs), to increase the number and the vasculogenic property of endothelial progenitor cells (EPCs) for enhanced vasculogenesis and tissue regeneration from a small amount of peripheral blood. Recently, the effect of microgravity (MG) was reported to enhance the potential of various stem cells. Therefore, we investigated whether combination of MG will enhance the function of our culture system. The purpose of this study was to evaluate the efficacy of MG on MNC-QQc to increase the number and function of peripheral blood EPCs.